Sedating antihistamines in children
Skin sensations local itching or burning sensation, flushing and a disagreeable heat.
Stomach pain acid secretion increases; small intestine contracts with crampy pain Respiratory - nose swelling, congestion, sneezing and wheezing.
The sedative effects of some foods such as milk and wheat in susceptible people is not blocked, but enhanced by antihistamines.
However, Seldane and Hismanal ran into big problems with adverse effects.We have drugs that selectively block both kinds of histamine receptors.The common antihistamines (Benadryl, Chlortripalon, Atarax, Claritin, Seldane, and Hismanal) are H1 blockers.The same mediators may sensitize nerve endings to other pain-producing mediators such as bradykinin.An initial burst of mediator activity will often set a series of cell responses in motion which will amplify and prolong disturbances.